Ivana Milicevic made its beginnings with the screen in the international success of Cameron Crowe Jerry Maguire (1996) and held one of the principal roles of the romantic comedy of Insane Mark S. Waters of him (Head Over Heels) (2001) at the sides of Monica Potter. One could also see it in Vanilla Sky (2001) of Cameron Crowe, Paycheck (2003) of John Woo, Love actually (2003) of Richard Curtis, Bye bye coils (Down with Love) (2002) of Peyton Reed, Ennemi of State (Enemy of the State) (1998) of Tony Scott, etc. Born in Sarajevo, of Bosniaque origin, it emigrates in Michigan at the five years age and starts to pose during its secondary studies. It starts at its exit of the college an international career which will lead it to New York, Los Angeles and Milan, and makes its beginnings of actress with the cabaret. Discovered by an agent in legendary "the Comedy Blind", it takes down a small role in the series Seinfeld (1990) and makes its first appearance with the screen in Jerry Maguire (1996). Ivana Milicevic held the high-speed motorboat of the series The Mind of the Married Man and played of the recurring roles in One one One, Nash Bridges (1996) and Felicity (1998).

She turned in guest star in series as various as a Nanny of hell (The Nanny) (1993), Las Vegas (2003), Charmed (1998), Buffy against the vampires (Buffy the Vampire Slayer) (1997), Experts: Miami (CSI: Miami) (2002), etc. She played more recently in And if it were true... (Just Like Heaven) (2005) of Mark Toilets. Ivana Milicevic is one of the principal actresses of the series Private diary of a married man. It was the guest star of Friends (1994) and Here! and turned the Frankenstein telefilm according to Dean Koontz.